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  2. Antimicrobial peptides - Wikipedia

    en.wikipedia.org/wiki/Antimicrobial_peptides

    Antimicrobial peptides from animals, plants and fungi organised by their secondary structure content. Circle size indicates overall molecular weight of each peptide. Antimicrobial peptides are a unique and diverse group of molecules, which are divided into subgroups on the basis of their amino acid composition and structure. [3]

  3. Imd pathway - Wikipedia

    en.wikipedia.org/wiki/Imd_pathway

    It is thought that plant-feeding aphids have lost Imd signalling as they bear a number of bacterial endosymbionts, including both nutritional symbionts that would be disrupted by aberrant expression of antimicrobial peptides, and defensive symbionts that cover for some of the immune deficiency caused by loss of Imd signalling. [26]

  4. Vitamin D - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D

    Vitamin D deficiency and insufficiency have been associated with adverse outcomes in COVID-19. [134] [135] ... (Cathelicidin Antimicrobial Peptide), ...

  5. Immune system - Wikipedia

    en.wikipedia.org/wiki/Immune_system

    Although cellular studies indicate that vitamin D has receptors and probable functions in the immune system, there is no clinical evidence to prove that vitamin D deficiency increases the risk for immune diseases or vitamin D supplementation lowers immune disease risk. [94]

  6. Vitamin D deficiency - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D_deficiency

    Mapping of several bone diseases onto levels of vitamin D (calcidiol) in the blood [6] Normal bone vs. osteoporosis. Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body.

  7. Hepcidin - Wikipedia

    en.wikipedia.org/wiki/Hepcidin

    Hepcidin is a protein that in humans is encoded by the HAMP gene. Hepcidin is a key regulator of the entry of iron into the circulation in mammals. [6]During conditions in which the hepcidin level is abnormally high, such as inflammation, serum iron falls due to iron trapping within macrophages and liver cells and decreased gut iron absorption.

  8. Keratinocyte - Wikipedia

    en.wikipedia.org/wiki/Keratinocyte

    A number of structural proteins (filaggrin, keratin), enzymes (e.g. proteases), lipids, and antimicrobial peptides contribute to maintain the important barrier function of the skin. Keratinization is part of the physical barrier formation ( cornification ), in which the keratinocytes produce more and more keratin and undergo terminal ...

  9. Cathelicidin antimicrobial peptide - Wikipedia

    en.wikipedia.org/wiki/Cathelicidin_antimicrobial...

    Cathelicidin peptides have been isolated from many different species of mammals, including marsupials. [6] Cathelicidins are mostly found in neutrophils, monocytes, mast cells, dendritic cells and macrophages [7] after activation by bacteria, viruses, fungi, parasites or the hormone 1,25-D, which is the hormonally active form of vitamin D. [8]