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Design of Experiments: A systematic, rigorous approach to engineering problem-solving that applies principles and techniques at the data collection stage so as to ensure the generation of valid, defensible, and supportable engineering conclusions [1] Design Point: A single combination of settings for the independent variables of an experiment.
A scientific control is an experiment or observation designed to minimize the effects of variables other than the independent variable (i.e. confounding variables). [1] This increases the reliability of the results, often through a comparison between control measurements and the other measurements.
Scientific misconduct is the violation of the standard codes of scholarly conduct and ethical behavior in the publication of professional scientific research.A Lancet review on Handling of Scientific Misconduct in Scandinavian countries gave examples of policy definitions.
Originally understood as the "fight-or-flight" response in Cannon's research, [3] the state of hyperarousal results in several responses beyond fighting or fleeing. This has led people to calling it the "fight, flight, freeze" response, "fight-flight-freeze-fawn" [ 1 ] [ citation needed ] or "fight-flight-faint-or-freeze", among other variants.
Index inducer or just inducer predictably induce metabolism via a given pathway and are commonly used in prospective clinical drug-drug interaction studies. [2] Strong, moderate, and weak inducers are drugs that decreases the AUC of sensitive index substrates of a given metabolic pathway by ≥80%, ≥50% to <80%, and ≥20% to <50% ...
The use of a sequence of experiments, where the design of each may depend on the results of previous experiments, including the possible decision to stop experimenting, is within the scope of sequential analysis, a field that was pioneered [13] by Abraham Wald in the context of sequential tests of statistical hypotheses. [14]
A variable in an experiment which is held constant in order to assess the relationship between multiple variables [a], is a control variable. [2] [3] A control variable is an element that is not changed throughout an experiment because its unchanging state allows better understanding of the relationship between the other variables being tested. [4]
In some experiments, a researcher may want to control and synchronize the time when a group of cells progress to the next phase of the cell cycle. [5] The cells can be induced to arrest as they arrive (at different time points) at a certain phase, so that when the arrest is lifted (for instance, rescuing cell cycle progression by introducing another chemical) all the cells resume cell cycle ...