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An important gene for adolescent-onset schizophrenia is the catechol-O-methyltransferase gene, a gene that regulates dopamine. [30] Children with schizophrenia have an increase in genetic deletions or duplication mutations [31] and some have a specific mutation called 22q11 deletion syndrome, which accounts for up to 2% of cases. [32] [33]
Symptoms are described in terms of positive, negative, and cognitive symptoms. [3] [35] The positive symptoms of schizophrenia are the same for any psychosis and are sometimes referred to as psychotic symptoms. These may be present in any of the different psychoses and are often transient, making early diagnosis of schizophrenia problematic.
The following diagnostic systems and rating scales are used in psychiatry and clinical psychology.This list is by no means exhaustive or complete. For instance, in the category of depression, there are over two dozen depression rating scales that have been developed in the past eighty years.
The name refers to the two types of symptoms in schizophrenia, as defined by the American Psychiatric Association: positive symptoms, which refer to an excess or distortion of normal functions (e.g., hallucinations and delusions), and negative symptoms, which represent a diminution or loss of normal functions. Some of these functions which may ...
The updated version is intended to be fully aligned with DSM-5, and includes changes in symptoms and organization of symptoms (e.g., in the trauma section, with post-traumatic stress disorder), changes in the diagnostic summary criteria (e.g., adding mixed hypomania and mixed depression to the mood disorders sections), and changes in the ...
The K-SADS (or Kiddie-SADS) is a version of the SADS adapted for school-aged children of 6–18 years. There are various different versions of the K-SADS, each varying slightly in terms of disorders and specific symptoms covered, as well as the scale range used.
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