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In the empirical sciences, the so-called three-sigma rule of thumb (or 3 σ rule) expresses a conventional heuristic that nearly all values are taken to lie within three standard deviations of the mean, and thus it is empirically useful to treat 99.7% probability as near certainty.
The standard deviation of the distribution is (sigma). A random variable with a Gaussian distribution is said to be normally distributed , and is called a normal deviate . Normal distributions are important in statistics and are often used in the natural and social sciences to represent real-valued random variables whose distributions are not ...
Fluorouracil (5-FU, 5-fluorouracil), sold under the brand name Adrucil among others, is a cytotoxic chemotherapy medication used to treat cancer. [3] By intravenous injection it is used for treatment of colorectal cancer , oesophageal cancer , stomach cancer , pancreatic cancer , breast cancer , and cervical cancer . [ 3 ]
The dose schedule given every two weeks is as follows: [5] Day 1–2: Oxaliplatin 100 mg/m 2 IV infusion, given as a 120 minutes IV infusion in 500 mL D5W, concurrent with leucovorin 400 mg/m 2 (or levoleucovorin 200 mg/m 2) IV infusion, followed by 5-FU 400 mg/m 2 IV bolus, followed by 46-hour 5-FU infusion (2400 mg/m 2 for first two cycles, and may be increased to 3000 mg/m 2 if tolerated by ...
Fluorouracil (5-FU) Tegafur; Some metabolites of these drugs, such as 5-fluorodeoxyuridylate monophosphate, also have fluoropyrimidine structures in the general sense of the term, but the more specific meaning is typically reserved for substances used as pharmaceuticals.
weak to strong (usually 3 or 4) 1500 1580 1600 C≡C terminal alkynes 2100–2140 weak disubst. alkynes 2190–2260 very weak (often indistinguishable) C=O aldehyde/ketone saturated aliph./cyclic 6-membered 1720 α,β-unsaturated 1685 aromatic ketones 1685 cyclic 5-membered 1750 cyclic 4-membered 1775 aldehydes 1725
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]