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Side effects of estradiol valerate include breast tenderness, breast enlargement, nausea, headache, and fluid retention. [15] [13] [14] Estradiol valerate is an estrogen and hence is an agonist of the estrogen receptor, the biological target of estrogens like estradiol. [5] [4] [16] It is an estrogen ester and a prodrug of estradiol in the body.
List of side effects of estradiol which may occur as a result of its use or have been associated with estrogen and/or progestogen therapy includes: [1] [2]. Gynecological: changes in vaginal bleeding, dysmenorrhea, increase in size of uterine leiomyomata, vaginitis including vaginal candidiasis, changes in cervical secretion and cervical ectropion, ovarian cancer, endometrial hyperplasia ...
Side effects of estradiol in women include breast tenderness, breast enlargement, headache, fluid retention, and nausea among others. [ 11 ] [ 20 ] Men and children who are exposed to estradiol may develop symptoms of feminization , such as breast development and a feminine pattern of fat distribution , and men may also experience low ...
A report in September 2009, from Health and Human Services' Agency for Healthcare Research and Quality suggests that tamoxifen and raloxifene used to treat breast cancer, significantly reduce invasive breast cancer in midlife and older women, but also increase the risk of adverse side effects. [21]
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
Upper-limb dysfunction is a common side effect of breast cancer treatment. [65] Shoulder range of motion can be impaired after surgery. Exercise can meaningfully improve should range of motion in women with breast cancer. [65] An exercise programme can be started early after surgery, if it does not negatively affect wound drainage. [65] [66] [67]
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