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Toxicodynamics, termed pharmacodynamics in pharmacology, describes the dynamic interactions of a toxicant with a biological target and its biological effects. [1] A biological target , also known as the site of action, can be binding proteins, ion channels , DNA , or a variety of other receptors.
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It is an application of pharmacokinetics to determine the relationship between the systemic exposure of a compound and its toxicity.It is used primarily for establishing relationships between exposures in toxicology experiments in animals and the corresponding exposures in humans.
Toxicodynamics (TD) and pharmacodynamics (PD) link a therapeutic agent or toxicant, or toxin (xenobiotic)'s dosage to the features, amount, and time course of its biological action. [11] The mechanism of action is a crucial factor in determining effect and toxicity of the drug, taking in consideration the pharmacokinetic (PK) factors. [12]
This is a list of films and television programs dubbed into indigenous languages. Indigenous language dubs are often made to promote language revitalisation and usage of the language. The number of films and television programs being dubbed into indigenous languages is growing, particularly in Australia, Canada, New Zealand and the United States.
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The terms dub, dubs, or dubbing commonly refer to: Accolade (also known as dubbing), a central act in rite of passage ceremonies conferring knighthood Dub music , a subgenre of reggae music
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