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Wide range of infections; penicillin used for streptococcal infections, syphilis, and Lyme disease: Gastrointestinal upset and diarrhea; Allergy with serious anaphylactic reactions; Brain and kidney damage (rare) Same mode of action as other beta-lactam antibiotics: disrupt the synthesis of the peptidoglycan layer of bacterial cell walls ...
Benzylpenicillin, also known as penicillin G (PenG [4]) or BENPEN, [5] is an antibiotic used to treat a number of bacterial infections. [6] This includes pneumonia , strep throat , syphilis , necrotizing enterocolitis , diphtheria , gas gangrene , leptospirosis , cellulitis , and tetanus . [ 6 ]
Penicillin G (benzylpenicillin) was first produced from a penicillium fungus that occurs in nature. The strain of fungus used today for the manufacture of penicillin G was created by genetic engineering to improve the yield in the manufacturing process. None of the other natural penicillins (F, K, N, X, O, U1 or U6) are currently in clinical use.
β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.
The β-lactam core structures. (A) A penam.(B) A carbapenam.(C) An oxapenam.(D) A penem.(E) A carbapenem.(F) A monobactam.(G) A cephem.(H) A carbacephem.(I) An oxacephem. This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class.
Benzathine benzylpenicillin, also known as benzathine penicillin G (BPG), is an antibiotic medication useful for the treatment of a number of bacterial infections. [3] Specifically it is used to treat strep throat, diphtheria, syphilis, and yaws. [3] [5] It is also used to prevent rheumatic fever. [5] It is given by injection into a muscle.
The recommended dosage for oral penicillin is 5 to 10 mg per pound of body weight, once daily. The duration of the treatment typically ranges from seven to 14 days, but in some cases, longer ...
It is a form of penicillin which is a salt of benzylpenicillin and the local anaesthetic agent procaine. [9] The salt has weak solubility, and is prepared as a suspension. Upon injection it forms a deposit within tissue (a "depot'), and the salt slowly dissolves into interstitial fluid - dissociating the two molecules into their bioactive forms over an extended pe
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