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The recommended dietary allowance for adults is 16 milligrams of niacin for adult men and 14 milligrams for adult women. Does niacin affect heart health? ... cholesterol and raise levels of HDL ...
Nicotinic acid increases apolipoprotein A1 levels by inhibiting the breakdown of this protein, which is a component of HDL particles. [ 35 ] [ 36 ] It also inhibits HDL-C hepatic uptake by suppressing production of the cholesterol ester transfer protein (CETP) gene. [ 28 ]
Epidemiological studies have shown that high concentrations of HDL (over 60 mg/dL) have protective value against cardiovascular diseases such as ischemic stroke and myocardial infarction. Low concentrations of HDL (below 40 mg/dL for men, below 50 mg/dL for women) increase the risk for atherosclerotic diseases. [16]
HDL cholesterol is between 40 and 59 for men, or 50 and 59 for women. Levels are high if: Total cholesterol is 240 or higher. LDL cholesterol is 160 or higher. HDL cholesterol is under 40 for men ...
Focusing on your HDL cholesterol can benefit your health, as a whole, according to doctors. Here are 8 easy ways you can increase your good fat numbers.
Liver disease or kidney disease: Niacin can accumulate in people with liver or kidney problems, potentially worsening their condition. [ 1 ] Bleeding disorders : Inositol nicotinate may slow blood clotting, increasing the risk of bleeding for individuals with clotting disorders or those undergoing surgery.