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Microsporidiosis is an opportunistic intestinal infection that causes diarrhea and wasting in immunocompromised individuals (HIV, for example). It results from different species of microsporidia, a group of microbial (unicellular) fungi. [1] In HIV-infected individuals, microsporidiosis generally occurs when CD4+ T cell counts fall below 150.
Enterocytozoon bieneusi, commonly known as microsporidia, is a unicellular, obligate intracellular eukaryote.Their life cycle includes a proliferative merogonic stage, followed by a sporogonic stage resulting in small, environmentally resistant, infective spores, which is their transmission mode.
Microsporidia is a group of fungi that infect species across the animal kingdom, one species of which can cause microsporidiosis in immunocompromised human hosts. [ 30 ] Pneumocystis jirovecii (formerly known as Pneumocystis carinii ) is a fungus that causes pneumocystis pneumonia , a respiratory infection.
The Rad9-Rad1-Hus1 protein complex (also known as the 9-1-1 complex) in eukaryotes is recruited to sites of DNA damage where it is considered to help trigger the checkpoint-signaling cascade. Genes that code for heterotrimeric 9-1-1 are present in microsporidia. [28]
Microsporum audouinii is an anthropophilic fungus in the genus Microsporum. [1] It is a type of dermatophyte that colonizes keratinized tissues (primarily hair) causing infection. [ 2 ] The fungus is characterized by its spindle-shaped macroconidia (7–30 × 35–160 μm ), clavate microconidia (2.5–3.5 × 4–7 μm) as well as its pitted or ...
[1] [7] Systemic fungal infections are more serious and include cryptococcosis, histoplasmosis, pneumocystis pneumonia, aspergillosis and mucormycosis. [3] Signs and symptoms range widely. [3] There is usually a rash with superficial infection. [2] Fungal infection within the skin or under the skin may present with a lump and skin changes. [3]
[1] [2] It has been considered a standard stain for the detection of spirochetes, [3] and is also used to stain Helicobacter pylori, Lawsonia intracellularis, [4] Microsporidia, [5] [6] and particulates. [7] It is also important for confirmation of Bartonella henselae, a causative organism in cat-scratch disease.
Malassezia furfur is a unicellular organism which varies in size between 1.5 and 4.5 × 2.0–6.5 micrometers. The cells have a bottle-like shape due to a small protrusion visible at the end of each cell. Cells are difficult to grow in a lab since they require specific conditions. [7]