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Cleaning validation is the methodology used to assure that a cleaning process removes chemical and microbial residues of the active, inactive or detergent ingredients of the product manufactured in a piece of equipment, the cleaning aids utilized in the cleaning process and the microbial attributes.
Method of lines - the example, which shows the origin of the name of method. The method of lines (MOL, NMOL, NUMOL [1] [2] [3]) is a technique for solving partial differential equations (PDEs) in which all but one dimension is discretized.
Explicit methods calculate the state of a system at a later time from the state of the system at the current time, while implicit methods find a solution by solving an equation involving both the current state of the system and the later one.
Verification is intended to check that a product, service, or system meets a set of design specifications. [6] [7] In the development phase, verification procedures involve performing special tests to model or simulate a portion, or the entirety, of a product, service, or system, then performing a review or analysis of the modeling results.
The Crank–Nicolson stencil for a 1D problem. In mathematics, especially the areas of numerical analysis concentrating on the numerical solution of partial differential equations, a stencil is a geometric arrangement of a nodal group that relate to the point of interest by using a numerical approximation routine.
In mathematics, the method of characteristics is a technique for solving partial differential equations. Typically, it applies to first-order equations , though in general characteristic curves can also be found for hyperbolic and parabolic partial differential equation .
Often, theory can establish the existence of a change of variables, although the formula itself cannot be explicitly stated. For an integrable Hamiltonian system of dimension , with ˙ = / and ˙ = /, there exist integrals .
In certain cases, von Neumann stability is necessary and sufficient for stability in the sense of Lax–Richtmyer (as used in the Lax equivalence theorem): The PDE and the finite difference scheme models are linear; the PDE is constant-coefficient with periodic boundary conditions and has only two independent variables; and the scheme uses no ...
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