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  2. Whose cardiovascular health do SGLT2, GLP-1 diabetes ... - AOL

    www.aol.com/whose-cardiovascular-health-sglt2...

    The researchers found that both SGLT2 inhibitors and GLP-1 agonists were associated with a lower risk of major cardiovascular events, but the drug effects varied with the patients’ age.

  3. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    Dapagliflozin is an example of an SGLT-2 inhibitor, it is a competitive, highly selective inhibitor of SGLT. It acts via selective and potent inhibition of SGLT-2, and its activity is based on each patient's underlying blood sugar control and kidney function. The results are decreased kidney reabsorption of glucose, glucosuria effect increases ...

  4. Sodium-glucose transport proteins - Wikipedia

    en.wikipedia.org/wiki/Sodium-glucose_transport...

    SGLT2 inhibitors, also called gliflozins, [14] are used in the treatment of type 2 diabetes. SGLT2 is only found in kidney tubules and in conjunction with SGLT1 resorbs glucose into the blood from the forming urine. By inhibiting SGLT2, and not targeting SGLT1, glucose is excreted which in turn lowers blood glucose levels.

  5. Sotagliflozin - Wikipedia

    en.wikipedia.org/wiki/Sotagliflozin

    Sotagliflozin, sold under the brand name Inpefa among others, is a medication used to reduce the risk of death due to heart failure. [1] It is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. [1] It is taken by mouth. [1] The most common side effect is genital infection in women. [2]

  6. Sodium/glucose cotransporter 2 - Wikipedia

    en.wikipedia.org/wiki/Sodium/glucose_cotransporter_2

    SGLT2 is a member of the sodium glucose cotransporter family, which are sodium-dependent glucose transport proteins. SGLT2 is the major cotransporter involved in glucose reabsorption in the kidney. [6] SGLT2 is located in the early proximal tubule, and is responsible for reabsorption of 80-90% of the glucose filtered by the kidney glomerulus. [7]

  7. Type 2 diabetes drugs could lower dementia, Parkinson's ... - AOL

    www.aol.com/type-2-drugs-could-lower-133000670.html

    The analysis showed that over a follow-up period of an average of 2.06 years for people on SGLT2 inhibitors, and 3.70 years for people on different antidiabetes drugs, there was a reduction in the ...

  8. Canagliflozin - Wikipedia

    en.wikipedia.org/wiki/Canagliflozin

    Canagliflozin is indicated to be used with diet and exercise to lower blood sugar in adults with type 2 diabetes; to reduce the risk of major heart-related events such as heart attack, stroke, or death in people with type 2 diabetes who have known heart disease; and to reduce the risk of end-stage kidney disease, worsening of kidney function, heart-related death, and being hospitalized for ...

  9. A Common Drug Could Lower Your Dementia Risk By 35 ... - AOL

    www.aol.com/common-drug-could-lower-dementia...

    A recent study found that a class of medications called SGLT-2 inhibitors—which does not include Ozempic or similar drugs like Zepbound—significantly lowered the risk of dementia in people ...