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  2. Nicotine vaccine - Wikipedia

    en.wikipedia.org/wiki/Nicotine_vaccine

    Nicotine vaccine is a novel immunological strategy for treating nicotine addiction. [1] Nicotine vaccine uses active immunization as the methodology to create polyclonal antibodies to the antigens, which is then used to treat drug abuse. [ 2 ]

  3. Tobacco Products Directive - Wikipedia

    en.wikipedia.org/wiki/Tobacco_Products_Directive

    The nicotine strength of e-liquids to no more than 20 mg/ml and require products containing nicotine and their packaging to be tamper proof and resistant to child tampering. The new regulation prohibited the use of certain ingredients that included taurine, colourings, and caffeine, the mandatory use of new labelling and health warning signs on ...

  4. Nicotine - Wikipedia

    en.wikipedia.org/wiki/Nicotine

    Nicotine is a secondary metabolite produced in a variety of plants in the family Solanaceae, most notably in tobacco Nicotiana tabacum, where it can be found at high concentrations of 0.5 to 7.5%. [178] Nicotine is also found in the leaves of other tobacco species, such as Nicotiana rustica (in amounts of 2–14%).

  5. Smoking in the United Kingdom - Wikipedia

    en.wikipedia.org/wiki/Smoking_in_the_United_Kingdom

    It has been estimated by Cancer Research UK that smoking is the single greatest cause of preventable illness and early death, with around 107,000 people dying in 2007 from smoking-related diseases, including cancers, in the UK. Around 86% of lung cancer deaths in the UK are caused by tobacco smoking; overall tobacco smoking is estimated to be ...

  6. Nicotine poisoning - Wikipedia

    en.wikipedia.org/wiki/Nicotine_poisoning

    The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...

  7. Smoking cessation - Wikipedia

    en.wikipedia.org/wiki/Smoking_cessation

    In nicotine-dependent smokers, quitting smoking can lead to nicotine withdrawal symptoms such as nicotine cravings, anxiety, irritability, depression, and weight gain. [23]: 2298 Professional smoking cessation support methods generally attempt to address nicotine withdrawal symptoms to help the person break free of nicotine addiction.

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  9. Smokeless tobacco - Wikipedia

    en.wikipedia.org/wiki/Smokeless_tobacco

    Furthermore, nicotine is absorbed by the body to different degrees depending on the pH level of the product, which is known as the free nicotine or unionized nicotine level. [ citation needed ] Below are some measured nicotine levels of various smokeless tobacco products from 2006 and 2007 and their corresponding free nicotine levels as ...