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Atipamezole, sold under the brand name Antisedan among others, is a synthetic α 2 adrenergic receptor antagonist used for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. Its reversal effect works by competing with the sedative for α 2-adrenergic receptors and displacing them.
Serotonin (5-HT3) receptor antagonists can be administered as a single dose at the end of surgery. Adverse effects include prolongation of the QT interval on electrocardiogram (EKG). Medications include ondansetron, granisetron, and dolasetron. Anticholinergics can be used as a long-acting patch placed behind the patient's ear. Adverse effects ...
Colostrum (from Latin, of unknown origin) is the first form of milk produced by the mammary glands of humans and other mammals immediately following delivery of the newborn. [1] Animal colostrum may be called beestings, the traditional word from Old English dialects. [2] Most species will begin to generate colostrum just prior to giving birth.
During the final month of gestation, alloantibodies concentrate into the colostrum. Horses, unlike humans, have an epitheliochorial placenta which prevents the transfer of antibodies to the foal in-utero. Foals are only exposed when they first nurse and ingest colostrum, so therefore are born without the disease and acquire it soon after birth.
Typical milk fever posture; cow in sternal recumbency with its head tucked into its flank. Milk fever, postparturient hypocalcemia, or parturient paresis is a disease, primarily in dairy cattle [1] but also seen in beef cattle and non-bovine domesticated animals, [2] characterized by reduced blood calcium levels (hypocalcemia).
Oxytocin contracts the smooth muscle of the uterus during and after birth, and during orgasm(s). After birth, oxytocin contracts the smooth muscle layer of band-like cells surrounding the alveoli to squeeze the newly produced milk into the duct system. Oxytocin is necessary for the milk ejection reflex, or let-down, in response to suckling, to ...
Colostrum also contains multiple immune modulating molecules, including high antibody levels. [19] Based on studies noting an overlap in the observed in vitro effects between a molecule contained in colostrum called colostrinin and the dialyzable leukocyte extract mentioned above, a hypothesis formed that the two were the same. [20]
The lethal dose for 50% of dogs is 100 – 200 mg per kilogram (kg) of body weight, yet some dogs will exhibit signs of toxicosis after ingesting as little as 20 mg per kg. [38] In case of accidental intake of chocolate, especially involving a smaller dog, contact a veterinarian or animal poison control immediately; it is commonly recommended ...