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Experimental Hematology is a peer-reviewed medical journal of hematology, which publishes original research articles and reviews, as well as the abstracts of the annual proceedings of the Society for Hematology and Stem Cells (formerly known as the International Society for Experimental Hematology).
The AUC (area under the curve) of the ROC curve reflects the overall accuracy and the separation performance of the biomarker (or biomarkers), [3] and can be readily used to compare different biomarker combinations or models. [4] As a rule of thumb, the fewer the biomarkers that one uses to maximize the AUC of the ROC curve, the better.
The Society for Hematology and Stem Cells (formerly the International Society for Experimental Hematology) is a learned society which deals with hematology, the study of the blood system and its diseases, including those caused by exposure to nuclear radiation.
Jacobs Journal of Aquaculture and Research; Jacobs Journal of Biochemistry; Jacobs Journal of Bioinformatics and Proteomics; Jacobs Journal of Biomarkers; Jacobs Journal of Biostatistics; Jacobs Journal of Biotechnology and Bioengineering; Jacobs Journal of Bone Marrow and Stem Cell Research; Jacobs Journal of Cancer Science and Research
Biomarker discovery is a medical term describing the process by which biomarkers are discovered. Many commonly used blood tests in medicine are biomarkers. There is interest in biomarker discovery on the part of the pharmaceutical industry; blood-test or other biomarkers could serve as intermediate markers of disease in clinical trials, and as possible drug targets.
A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule." [18] In cancer research and medicine, biomarkers are used in three primary ways: [19] To help diagnose conditions, as in the case of identifying early stage cancers (diagnostic)
In biomedical contexts, a biomarker, or biological marker, is a measurable indicator of some biological state or condition. Biomarkers are often measured and evaluated using blood, urine, or soft tissues [1] to examine normal biological processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. [2]
In medicine, a biomarker is a measurable indicator of the severity or presence of some disease state. It may be defined as a "cellular, biochemical or molecular alteration in cells, tissues or fluids that can be measured and evaluated to indicate normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention."