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Sarolaner, sold under the brand name Simparica, is an ectoparasiticide veterinary medication for the treatment of flea and tick infestations in dogs. [7] [8] It is also used off-label to control sarcoptic mange and demodectic mange. [8] Sarolaner is also a component of the combination drug Simparica Trio, which contains sarolaner, moxidectin ...
The isoxazoline class of insecticides was discovered by Nissan. They act by allosterically modulating GABA-gated chloride channels. (IRAC group 30).Four (Fluralaner, Lotilaner, Afoxolaner and Sarolaner) are used against fleas in dogs and cats, whereby foxalaner and sarolaner are only approved for dogs. [2]
Apples are safe for dogs, but apple seeds are not. Apple seeds, persimmon, peach, and plum pits, as well as other fruit seeds or pits have "cyanogenic glycosides". For example, if an apple seed skin is broken as a dog eats an apple, then cyanide could be released. Apple seeds should be removed before a dog eats the apple. [citation needed]
According to clinical studies performed prior to marketing: The oral toxicity profile of afoxolaner consists of a diuretic effect (rats only), effects secondary to a reduction in food consumption (rats and rabbits only) and occasional vomiting and/or diarrhea (dogs, 120 and 200 mg/kg bodyweight (bw)) following high oral doses.
A new federal report shows that one drink per day could raise the risk of liver damage and several cancers. The report follows a recommendation by the U.S. Surgeon General on safe alcohol ...
For dogs who are sensitive to lactose, a vegan puppuccino made from oat or soya may be a better option. Dairy is one of the more common food allergies in pets , so an alternative milk might be a ...
amitriptyline – tricyclic antidepressant used to treat separation anxiety, excessive grooming dogs and cats; amlodipine – calcium channel blocker used to decrease blood pressure; amoxicillin – antibacterial; apomorphine – emetic (used to induce vomiting) artificial tears – lubricant eye drops used as a tear supplement
This dog-safe toothpaste is certified by the Veterinary Oral Health Council and was voted as the best product in our buying guide. It comes in three delicious flavors and helps to reduce plaque ...