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Coronary artery disease (CAD) or ischemic heart disease are the terms used to describe narrowing of the coronary arteries. [8] As the disease progresses, plaque buildup can partially block blood flow to the heart muscle. Without enough blood supply , the heart is unable to work properly, especially under increased stress.
The relatively narrow coronary arteries are commonly affected by atherosclerosis and can become blocked, causing angina or a heart attack. The coronary arteries are classified as "terminal circulation", since they represent the only source of blood supply to the myocardium; there is very little redundant blood supply, that is why blockage of ...
The arteries that bring blood to the privates can be damaged by atherosclerosis, just like the coronary arteries that bring blood to the heart. Since the arteries to the privates are smaller than ...
Coronary artery disease develops when the arteries that supply your heart become clogged with a fatty substance called plaque. The build-up of plaque is also called atherosclerosis.
The thrombus deposits on the ruptured plaque to completely block the coronary artery, halting oxygen supply to cardiomyocytes. Under hypoxia, cardiomyocytes perform anaerobic respiration, producing more lactate. [34] [36] With blocked coronary circulation, lactate clearance from cardiomyocytes is also hindered. [36]
Those symptoms can also come as a result of a coronary artery spasm, which occurs when an artery in the heart squeezes shut. Clogged arteries can cause those events, as well. 4.