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  2. Metformin - Wikipedia

    en.wikipedia.org/wiki/Metformin

    Gastrointestinal upset can cause severe discomfort; it is most common when metformin is first administered, or when the dose is increased. [76] [81] The discomfort can often be avoided by beginning at a low dose (1.0 to 1.7 g/day) and increasing the dose gradually, but even with low doses, 5% of people may be unable to tolerate metformin.

  3. Drug intolerance - Wikipedia

    en.wikipedia.org/wiki/Drug_intolerance

    In other words, in a person that is intolerant to a medication, it is possible for a dose of 10 mg to "feel" like a dose of 100 mg, resulting in an overdose—a "normal" dose can be a "toxic" dose in these individuals, leading to clinically significant effects. There is also an aspect of drug intolerance that is subjective.

  4. How Long Will It Take to Lose Weight on Metformin?

    www.aol.com/long-does-metformin-weight-loss...

    Among the 199 participants, 154 took a daily dose of up to 2,500mg of metformin for six months — the average metformin dose was 2,230mg daily. The remaining 45 participants weren’t treated ...

  5. When Is the Best Time to Take Metformin? - AOL

    www.aol.com/lifestyle/best-time-metformin...

    The best time depends on your metformin type and dosage. Extended-release metformin tablets are usually taken once a day with your evening meal. Some people take metformin once, twice, or even ...

  6. 6 Benefits of Taking Metformin (Besides Weight Loss) - AOL

    www.aol.com/lifestyle/6-benefits-taking...

    2. Alleviates Hunger. Metformin improves how well your cells respond to insulin. This helps regulate your blood sugar levels and manage spikes in insulin that can trigger hunger and food cravings.

  7. Tolerability - Wikipedia

    en.wikipedia.org/wiki/Tolerability

    Tolerability refers to the degree to which overt adverse effects of a drug can be tolerated by a patient. [1] Tolerability of a particular drug can be discussed in a general sense, or it can be a quantifiable measurement as part of a clinical study.

  8. Vildagliptin/metformin - Wikipedia

    en.wikipedia.org/wiki/Vildagliptin/metformin

    Vildagliptin/metformin is indicated in the treatment of type-2 diabetes mellitus: [4] [6] [7] it is indicated in the treatment of adults who are unable to achieve sufficient glycaemic control at their maximally tolerated dose of oral metformin alone or who are already treated with the combination of vildagliptin and metformin as separate tablets.

  9. 15 Alternatives to Ozempic for Weight Loss - AOL

    www.aol.com/15-alternatives-ozempic-weight-loss...

    Oral weight loss medications like metformin and Topamax. Drug-free weight loss options like eating nutritious foods and doing more movement ... Your dose might start at 3.75mg of phentermine and ...