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For most people, recommendations are to reduce blood pressure to less than or equal to somewhere between 140/90 mmHg and 160/100 mmHg. [2] In general, for people with elevated blood pressure, attempting to achieve lower levels of blood pressure than the recommended 140/90 mmHg will create more harm than benefits, [3] in particular for older people. [4]
The effect of treatment of blood pressure between 130/80 mmHg and 160/100 mmHg is less clear, with some reviews finding benefit [6] [16] [17] and others finding unclear benefit. [18] [19] [20] High blood pressure affects 33% of the population globally. [9] About half of all people with high blood pressure do not know that they have it. [9]
As atrial fibrillation becomes more persistent, the junction between the pulmonary veins and the left atrium becomes less of an initiator and the left atrium becomes an independent source of arrhythmias. [18] High blood pressure and valvular heart disease are the most common modifiable risk factors for AF.
For people with high blood pressure, higher heart rate variability (HRV) is a risk factor for atrial fibrillation. [51] Both high systolic pressure and high pulse pressure (the numerical difference between systolic and diastolic pressures) are risk factors. [49]
As of 2018, the best available evidence favors low-dose thiazide diuretics as the first-line treatment of choice for high blood pressure when drugs are necessary. [5] Although clinical evidence shows calcium channel blockers and thiazide-type diuretics are preferred first-line treatments for most people (from both efficacy and cost points of ...
Three risk factors — high blood pressure, smoking and atrial fibrillation (which is an irregular heart rhythm) were linked with higher risk of severe compared to mild-moderate stroke,” said Dr ...