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Taking certain types of medications can contribute to gout. A couple examples include cyclosporine, an immunosuppressant drug, and diuretics. Lastly, dietary factors also increase gout risk.
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[8] [9] In those already on the medication, it should be continued even during an acute gout attack. [8] [6] While use during pregnancy does not appear to result in harm, this use has not been well studied. [1] Allopurinol is in the xanthine oxidase inhibitor family of medications. [7] Allopurinol was approved for medical use in the United ...
Levels that cannot be brought below 6.0 mg/dL while attacks continue indicates refractory gout. [68] While historically it is not recommended to start allopurinol during an acute attack of gout, this practice appears acceptable. [69] Allopurinol blocks uric acid production, and is the most commonly used agent. [20]
Benzbromarone is a uricosuric agent and non-competitive inhibitor of xanthine oxidase [1] used in the treatment of gout, especially when allopurinol, a first-line treatment, fails or produces intolerable adverse effects. It is structurally related to the antiarrhythmic amiodarone. [2]
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