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Antiphospholipid syndrome is known for causing arterial or venous blood clots, in any organ system, and pregnancy-related complications.While blood clots and pregnancy complications are the most common and diagnostic symptoms associated with APS, other organs and body parts may be affected like platelet levels, heart, kidneys, brain, and skin.
Livedo reticularis is a common skin finding consisting of a mottled reticulated vascular pattern that appears as a lace-like purplish discoloration of the skin. [1] The discoloration is caused by reduction in blood flow through the arterioles that supply the cutaneous capillaries, resulting in deoxygenated blood showing as blue discoloration ().
Catastrophic antiphospholipid syndrome (CAPS), also known as Asherson's syndrome, is a rare autoimmune disease in which widespread, intravascular clotting causes multi-organ failure. [1] The syndrome is caused by antiphospholipid antibodies that target a group of proteins in the body that are associated with phospholipids .
Livedoid vasculopathy has been linked to rheumatoid arthritis, systemic lupus erythematosus, scleroderma, polyarteritis nodosa, mixed and undifferentiated connective tissue diseases, and Sjogren's syndrome. Individuals with systemic lupus erythematosus who also have antiphospholipid antibody syndrome are more vulnerable. [9]
Splinter hemorrhages (or haemorrhages) are tiny blood clots that tend to run vertically under the nails.Splinter hemorrhages are not specific to any particular condition, and can be associated with subacute infective endocarditis, scleroderma, trichinosis, systemic lupus erythematosus (SLE), rheumatoid arthritis, psoriatic nails, [1] antiphospholipid syndrome, [2]: 659 haematological ...
Retiform purpura is the result of total vascular blockage and damage to the skin's blood vessels.The skin then shows lesions, appearing due to intravascular issues where clots, proteins, or emboli block skin vessels.
Secondary anetoderma is a skin disease that develops in areas where there has previously been or is currently skin pathology. It has been linked to a variety of conditions, such as acne, [8] urticaria pigmentosa, [9] syphilis, [6] leprosy, [8] granuloma annulare, [10] insect bites, [11] and antiphospholipid syndrome. [12]
Other symptoms to note: Acne is the most common skin condition affecting Americans, Dr. Zeichner says, so you likely have experience with pimples already. The causes vary, but are often rooted in ...