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  2. Intravitreal injection - Wikipedia

    en.wikipedia.org/wiki/Intravitreal_injection

    Intravitreal injection was first mentioned in a study in 1911, in which the injection of air was used to repair a detached retina. [6] [7] [8] There were also investigations evaluating intravitreal antibiotics injection using sulfanilamide and penicillin to treat endophthalmitis in the 1940s, yet due to the inconsistency of results and safety concerns, this form of drug delivery was only for ...

  3. Anti-VEGF - Wikipedia

    en.wikipedia.org/wiki/Anti-VEGF

    This is done in the treatment of certain cancers and in age-related macular degeneration. They can involve monoclonal antibodies such as bevacizumab , antibody derivatives such as ranibizumab (Lucentis), or orally-available small molecules that inhibit the tyrosine kinases stimulated by VEGF: sunitinib , sorafenib , axitinib , and pazopanib ...

  4. FDA Approves Biosimilars for Macular Degeneration Treatment - AOL

    www.aol.com/fda-approves-biosimilars-macular...

    These drugs are approved to treat neovascular (wet) age-related macular degeneration, macular edema following retinal vein occlusion, diabetic macular edema and diabetic retinopathy. View the ...

  5. Pegaptanib - Wikipedia

    en.wikipedia.org/wiki/Pegaptanib

    Pegaptanib [2] sodium injection (brand name Macugen) is an anti-angiogenic medicine for the treatment of neovascular (wet) age-related macular degeneration (AMD). [3] It was discovered by NeXstar Pharmaceuticals (which merged with Gilead Sciences in 1999) and licensed in 2000 to EyeTech Pharmaceuticals, now OSI Pharmaceuticals, for late stage development and marketing in the United States.

  6. Astellas Institute for Regenerative Medicine - Wikipedia

    en.wikipedia.org/wiki/Astellas_Institute_for...

    Astellas Institute for Regenerative Medicine; Company type: Subsidiary: Industry: Biotechnology: Founded: 1994: Headquarters: Marlborough, MA: Products: Stem cell therapies for macular degeneration (human safety trial started in 2010 [1]), retinis pigmentosa, glaucoma and corneal blindness [2]

  7. Choroidal neovascularization - Wikipedia

    en.wikipedia.org/wiki/Choroidal_neovascularization

    Layers of the eye, with the choroid labelled. Choroidal neovascularization (CNV) is the creation of new blood vessels in the choroid layer of the eye.Choroidal neovascularization is a common cause of neovascular degenerative maculopathy (i.e. 'wet' macular degeneration) [1] commonly exacerbated by extreme myopia, malignant myopic degeneration, or age-related developments.

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