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  2. Alpha-1 antitrypsin - Wikipedia

    en.wikipedia.org/wiki/Alpha-1_antitrypsin

    Alpha-1 antitrypsin or α 1-antitrypsin (A1AT, α 1 AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the SERPINA1 gene. A protease inhibitor, it is also known as alpha 1 –proteinase inhibitor (A1PI) or alpha 1-antiproteinase (A1AP) because it inhibits various proteases (not just trypsin). [5]

  3. Proximal diabetic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Proximal_diabetic_neuropathy

    Proximal diabetic neuropathy, also known as diabetic amyotrophy, is a complication of diabetes mellitus that affects the nerves that supply the thighs, hips, buttocks and/or lower legs. Proximal diabetic neuropathy is a type of diabetic neuropathy characterized by muscle wasting, weakness, pain, or changes in sensation/numbness of the leg.

  4. Diabetic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Diabetic_neuropathy

    In the DCCT (Diabetes Control and Complications Trial, 1995) study, the annual incidence of neuropathy was 2% per year but dropped to 0.56% with intensive treatment of Type 1 diabetics. The progression of neuropathy is dependent on the degree of glycemic control in both Type 1 and Type 2 diabetes. Duration of diabetes, age, cigarette smoking ...

  5. Insulin Resistance: From Symptoms to Treatment - AOL

    www.aol.com/insulin-resistance-symptoms...

    Diabetic peripheral neuropathy is a group of conditions characterized by damage to nerves in the limbs, particularly the legs and feet. ... to help treat type 2 diabetes include: GLP-1 receptor ...

  6. Neuropathic arthropathy - Wikipedia

    en.wikipedia.org/wiki/Neuropathic_arthropathy

    Diabetes is the foremost cause in America today for neuropathic joint disease, [4] and the foot is the most affected region. In those with foot deformity, approximately 60% are in the tarsometatarsal joints (medial joints affected more than lateral), 30% metatarsophalangeal joints , and 10% have ankle disease.

  7. Protease inhibitor (biology) - Wikipedia

    en.wikipedia.org/wiki/Protease_inhibitor_(biology)

    In medicine, protease inhibitor is often used interchangeably with alpha 1-antitrypsin (A1AT, which is abbreviated PI for this reason). [3] A1AT is indeed the protease inhibitor most often involved in disease, namely in alpha-1 antitrypsin deficiency.

  8. Autonomic neuropathy - Wikipedia

    en.wikipedia.org/wiki/Autonomic_neuropathy

    Autonomic neuropathy (AN or AAN) is a form of polyneuropathy that affects the non-voluntary, non-sensory nervous system (i.e., the autonomic nervous system), affecting mostly the internal organs such as the bladder muscles, the cardiovascular system, the digestive tract, and the genital organs. These nerves are not under a person's conscious ...

  9. Alpha-1 antitrypsin deficiency - Wikipedia

    en.wikipedia.org/wiki/Alpha-1_antitrypsin_deficiency

    Alpha-1 antitrypsin deficiency (A1AD or AATD) is a genetic disorder that may result in lung disease or liver disease. [1] Onset of lung problems is typically between 20 and 50 years of age. [ 1 ] This may result in shortness of breath , wheezing , or an increased risk of lung infections .