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Cachexia (/ k ə ˈ k ɛ k s i ə / [1]) is a syndrome that happens when people have certain illnesses, causing muscle loss that cannot be fully reversed with improved nutrition. [2] It is most common in diseases like cancer, congestive heart failure, chronic obstructive pulmonary disease, chronic kidney disease, and AIDS.
Certain diseases can cause a complex muscle wasting syndrome known as cachexia. It is commonly seen in cancer, congestive heart failure , chronic obstructive pulmonary disease , chronic kidney disease and AIDS although it is associated with many disease processes, usually with a significant inflammatory component.
Some cancers can cause a systemic inflammatory state that leads to ongoing muscle loss and weakness, known as cachexia. [35] Some cancers, such as Hodgkin's disease, leukemias, and liver or kidney cancers, can cause a persistent fever. [32] Shortness of breath, called dyspnea, is a common symptom of cancer
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The causes listed are relatively immediate medical causes, but the ultimate cause of death might be described differently. For example, tobacco smoking often causes lung disease or cancer, and alcohol use disorder can cause liver failure or a motor vehicle accident.
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The preamble to this article notes that Cachexia is formally defined as "loss of body mass that cannot be reversed nutritionally." The 'Disease Settings' section observes "In most cases cachexia can be reversed with just eating" which flatly contradicts the definition given, and is factually incorrect.