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Common side effects when used as a cream are limited to the skin and include skin redness, peeling, and sun sensitivity. [10] When taken by mouth, side effects include hypertriglyceridemia, hypercholesterolemia, shortness of breath, headache, numbness, depression, skin dryness, itchiness, hair loss, vomiting, muscle pains, and vision changes. [8]
Toxic effects of retinoids occur with both acute or prolonged intake, depending on which retinoid is considered. The specific toxicity is related to the mechanism of action as well as exposure. A medical sign of chronic or acute poisoning with retinol is hypervitaminosis A , which includes the presence of painful tender swellings on the long bones.
Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Accutane among others, is a medication used to treat skin diseases like harlequin-type ichthyosis, and lamellar ichthyosis, and severe cystic acne or moderate acne that is unresponsive to antibiotics. [6]
Known by one of its brand names, Retin-A, tretinoin belongs to the synthetic retinoid class of medications. It comes in creams or gels and requires a prescription. ... Side effects include minor ...
Oral retinoids are also available. Isotretinoin is a powerful retinoid typically reserved for severe acne that hasn't responded to other treatments. It works by reducing oil production, unclogging ...
“Using formulations that are less irritating or have calming ingredients can help reduce side effects in sensitive skin types,” explains Azadeh Shirazi, M.D., ... Prescription retinoids: ...