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Since 2000, Flubendazole-treated grit has increasingly been laid out on a landscape-scale across many UK grouse-shooting moors by gamekeepers in an attempt to reduce the impact on bird numbers from strongyle worm. Evidence of high worm burden is required before a veterinarian can dispense and sell the product, known as 'medicated grit'. [6]
Another treatment that can be used is mebendazole, or flubendazole. [13] The medication interferes with the parasite’s nutrient intake, which eventually leads to death. However, it has been shown that both albendazole and mebendazole have low cure rate for Trichuris thrichiura specifically, with treatments only achieving cure rates 30,7% for ...
Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. [5] This includes ascariasis, pinworm infection, hookworm infections, guinea worm infections and hydatid disease, among others. [5] It has been used for treatment of giardiasis but is not a preferred agent.
For treatment against roundworms, drugs based on emodepside, fenbendazole, flubendazole, mebendazole, milbemycin oxime, moxidectin, pyrantel and selamectin are approved in Germany for domestic dogs. These drugs are broad-spectrum anthelmintics and also exert activity against most other nematodes found in dogs. [ 70 ]
Pinworm infection occurs worldwide, [10] and is the most common helminth (i.e., parasitic worm) infection in the United States and Western Europe. [18] In the United States, a study by the Center of Disease Control reported an overall incidence rate of 11.4% among people of all ages. [ 18 ]
All major gastrointestinal nematode genera survived treatment in various studies. In cattle, prevalence of anthelminthic resistance varied between anthelmintic classes from 0–100% (benzimidazoles and macrocyclic lactones), 0–17% (levamisole) and 0–73% (moxidectin), and both Cooperia and Ostertagia survived treatment. [14]