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[3] [4] Cannabidiol (CBD) is another major constituent of some cannabis plants. [5] Conversion of CBD to THC can occur when CBD is heated to temperatures between 250–300 °C (480 to 570°F), potentially leading to its partial transformation into THC. [6] At least 113 distinct cannabinoids have been isolated from cannabis. [7]
[11] [12] At least three independent methods have successfully converted CBD to THC. Despite the CBD and THC having the same molecular weight, multiple analytical methods are able to differentiate them. [11] "on the recovery of both THC (86.7−90.0%) and CBD (92.3−95.6%). The slightly lower recovery of THC can be explained by the fact that ...
Other cannabinoids include delta-8-tetrahydrocannabinol, cannabidiol (CBD), cannabinol (CBN), cannabicyclol (CBL), cannabichromene (CBC) and cannabigerol (CBG); they have less psychotropic effects than THC, but may play a role in the overall effect of cannabis. [9] The most studied are THC, CBD and CBN. [54]
Various strains of "medical cannabis" are found to have a significant variation in the ratios of CBD-to-THC and are known to contain other non-psychotropic cannabinoids. [44] Any psychoactive cannabis, regardless of its CBD content, is derived from the flower (or bud) of the genus Cannabis.
CBD shares a precursor with THC and is the main cannabinoid in CBD-dominant Cannabis strains. CBD has been shown to play a role in preventing the short-term memory loss associated with THC. [29] There is tentative evidence that CBD has an anti-psychotic effect, but research in this area is limited. [30] [24]
Laboratory experiments have suggested that cannabis and cannabinoids have anticarcinogenic and antitumor effects, [22] including a potential effect on breast- and lung-cancer cells. [23] While cannabis may have potential for refractory cancer pain or use as an antiemetic, much of the evidence comes from outdated or small studies, or animal ...
Typically, CBD products contain little to no THC and generally not enough to alter your mental state or make you fail a drug test. CBD is often derived from hemp, which can only contain 0.3 ...
THC is also an active ingredient in nabiximols, a specific extract of Cannabis that was approved as a botanical drug in the United Kingdom in 2010 as a mouth spray for people with multiple sclerosis to alleviate neuropathic pain, spasticity, overactive bladder, and other symptoms. [37]