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Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. [36][37] Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone.
Methylprednisolone. Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4][5][6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares. Methylprednisolone and its derivatives can ...
Prednisolone is a corticosteroid drug with predominant glucocorticoid and low mineralocorticoid activity, making it useful for the treatment of a wide range of inflammatory and autoimmune conditions [14] such as asthma, [15] uveitis, pyoderma gangrenosum, rheumatoid arthritis, urticaria, [16] angioedema, [16] ulcerative colitis, pericarditis, temporal arteritis and Crohn's disease, Bell's ...
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and ...
A separate list for children up to 12 years of age, known as the WHO Model List of Essential Medicines for Children (EMLc), was created in 2007 and is in its 9th edition. [ 10 ][ 21 ][ 22 ][ 23 ] It was created to make sure that the needs of children were systematically considered such as availability of proper formulations. [ 24 ][ 25 ...
Cyclophosphamide (Baxter's Cytoxan) is probably the most potent immunosuppressive compound. In small doses, it is very efficient in the therapy of systemic lupus erythematosus, autoimmune hemolytic anemias, granulomatosis with polyangiitis, and other immune diseases. High doses cause pancytopenia and hemorrhagic cystitis.
Methylprednisolone aceponate, or methylprednisolone acetate propionate, sold under the brand names Advantan and Avancort, is a glucocorticoid and a corticosteroid ester —specifically the C17α propionate and C21 acetate diester of methylprednisolone. [1][2][3] In Russia and some other countries the drug is available in 4 dosage forms ...
Methylprednisolone acetate, sold under the brand names Depo-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester —specifically the C21 acetate ester of methylprednisolone —which is used in clinical and veterinary medicine. [1][2][3][4][5][6][7] It has been formulated as an aqueous suspension for ...