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Prednisone is a synthetic glucocorticoid used for its anti-inflammatory and immunosuppressive properties. [36][37] Prednisone is a prodrug; it is metabolised in the liver by 11-β-HSD to prednisolone, the active drug. Prednisone has no substantial biological effects until converted via hepatic metabolism to prednisolone.
Drug nomenclature is the systematic naming of drugs, especially pharmaceutical drugs.In the majority of circumstances, drugs have 3 types of names: chemical names, the most important of which is the IUPAC name; generic or nonproprietary names, the most important of which are international nonproprietary names (INNs); and trade names, which are brand names. [1]
Methylprednisolone. Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4][5][6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares. Methylprednisolone and its derivatives can ...
Tall man lettering (tall-man lettering or tallman lettering) is the practice of writing part of a drug 's name in upper case letters to help distinguish sound-alike, look-alike drugs from one another in order to avoid medication errors. [1][2] For example, in tall man lettering, "prednisone" and "prednisolone" should be written "predniSONE" and ...
Methylprednisolone acetate, sold under the brand names Depo-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester —specifically the C21 acetate ester of methylprednisolone —which is used in clinical and veterinary medicine. [1][2][3][4][5][6][7] It has been formulated as an aqueous suspension for ...
Prednisolone is a corticosteroid drug with predominant glucocorticoid and low mineralocorticoid activity, making it useful for the treatment of a wide range of inflammatory and autoimmune conditions [14] such as asthma, [15] uveitis, pyoderma gangrenosum, rheumatoid arthritis, urticaria, [16] angioedema, [16] ulcerative colitis, pericarditis, temporal arteritis and Crohn's disease, Bell's ...
The name "11-deoxycortisol" is an example of a derived name that uses cortisol as a parent structure without an oxygen atom (hence "deoxy") attached to position 11 (as a part of a hydroxy group). [ 14 ] [ 21 ] The numbering of positions of carbon atoms in the steroid nucleus is set in a template found in the Nomenclature of Steroids [ 22 ] that ...
Methylprednisolone succinate. Methylprednisolone succinate, sold under the brand name Solu-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester —specifically the C21 succinate ester of methylprednisolone —which is used by intravenous administration. [3][4] Methylprednisolone succinate is provided as ...