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Bone autograft is generally preferred by surgeons because, as well as eliminating the risks associated with allografts, bone autograft contains native bone-forming cells (osteoblasts), so the graft itself forms new bone (osteoinductive), as well as acting as a matrix or scaffold to new bone growing from the bones being bridged (osteoconductive ...
An allograft contains many of the beneficial characteristics of nerve autograft, such as three-dimensional microstructural scaffolding and protein components inherent to nerve tissue. [3] One of the adverse effects of nerve allotransplantation is the immunogenic response.
Spinal fusion, also called spondylodesis or spondylosyndesis, is a surgery performed by orthopaedic surgeons or neurosurgeons that joins two or more vertebrae. [1] This procedure can be performed at any level in the spine (cervical, thoracic, lumbar, or sacral) and prevents any movement between the fused vertebrae.
Fusion [ edit ] When preparing to fuse the sacroiliac joint , a surgeon must consider the desired degree of invasiveness, surgical approach (fascial splitting that is posterior midline, posterior lateral, posterior lateral inferior, lateral, anterior), instrumentation, type of bone grafting material ( autograft , allograft , and xenograft ...
In orthopaedic medicine, a bone graft can be sourced from a patient's own bone in order to fill space and produce an osteogenic response in a bone defect. However, due to the donor-site morbidity associated with autograft, other methods such as bone allograft and bone morphogenetic proteins and synthetic graft materials are often used as alternatives.
Bone graft procedures consist of more than just the surgery itself. The complete three-month total cost of a complex posterolateral lumbar spine fusion bone graft supplemented with graft extenders ranges from a mean of approximately US$33,860 to US$37,227. [33] This price includes all visits in and out of the hospital for three months.
Autograft: graft taken from one part of the body of an individual and transplanted onto another site in the same individual, e.g., skin graft. Isograft: graft taken from one individual and placed on another individual of the same genetic constitution, e.g., grafts between identical twins.
To prevent the vertebrae from collapsing and to increase stability, the open space is often filled with a graft. That can be a bone graft, taken from the pelvis or cadaveric bone; or an artificial implant. [4] The slow process of the bone graft joining the vertebrae together is called "fusion".