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Some, but not all, carboxypeptidases are initially produced in an inactive form; this precursor form is referred to as a procarboxypeptidase. In the case of pancreatic carboxypeptidase A, the inactive zymogen form - pro-carboxypeptidase A - is converted to its active form - carboxypeptidase A - by the enzyme trypsin. This mechanism ensures that ...
Carboxypeptidase A2 is an enzyme that in humans is encoded by the CPA2 gene. [5] [6] [7]Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A1 and A2 forms are monomeric proteins with different biochemical properties.
CPA-1 and CPA-2 (and, it is presumed, all other CPAs) employ a zinc ion within the protein for hydrolysis of the peptide bond at the C-terminal end of an amino acid residue.
12873 Ensembl ENSG00000163751 ENSMUSG00000001865 UniProt P15088 P15089 RefSeq (mRNA) NM_001870 NM_007753 RefSeq (protein) NP_001861 NP_031779 Location (UCSC) Chr 3: 148.87 – 148.9 Mb Chr 3: 20.27 – 20.3 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Carboxypeptidase A3 (mast cell carboxypeptidase A), also known as CPA3, is an enzyme which in humans is encoded by the CPA3 gene ...
12876 Ensembl ENSG00000109472 ENSMUSG00000037852 UniProt P16870 Q00493 RefSeq (mRNA) NM_001873 NM_013494 RefSeq (protein) NP_001864 NP_038522 Location (UCSC) Chr 4: 165.36 – 165.5 Mb Chr 8: 65.05 – 65.15 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Carboxypeptidase E (CPE), also known as carboxypeptidase H (CPH) and enkephalin convertase, is an enzyme that in humans is encoded ...
1361 56373 Ensembl ENSG00000080618 ENSMUSG00000021999 UniProt Q96IY4 Q9JHH6 RefSeq (mRNA) NM_016413 NM_001278541 NM_001872 NM_019775 RefSeq (protein) NP_001265470 NP_001863 NP_062749 Location (UCSC) Chr 13: 46.05 – 46.11 Mb Chr 14: 75.48 – 75.52 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma ...
Carboxypeptidase U (EC 3.4.17.20, arginine carboxypeptidase, carboxypeptidase R, plasma carboxypeptidase B, thrombin-activatable fibrinolysis inhibitor) is an enzyme ...
71791 Ensembl n/a ENSMUSG00000039070 UniProt Q9UI42 Q6P8K8 RefSeq (mRNA) NM_016352 NM_001163446 NM_027926 RefSeq (protein) NP_001156918 NP_057436 NP_082202 Location (UCSC) n/a Chr 6: 30.57 – 30.59 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Carboxypeptidase A4 is an enzyme that in humans is encoded by the CPA4 gene. This gene is a member of the carboxypeptidase A/B subfamily ...