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E. W. Kemble's "Death's Laboratory" on the cover of Collier's (June 3, 1905). A patent medicine, also known as a proprietary medicine or a nostrum (from the Latin nostrum remedium, or "our remedy") is a commercial product advertised to consumers as an over-the-counter medicine, generally for a variety of ailments, without regard to its actual effectiveness or the potential for harmful side ...
E. W. Kemble's "Death's Laboratory" on the cover of the 3 June 1905 edition of Collier's. A patent medicine (sometimes called a proprietary medicine) is a non-prescription medicine or medicinal preparation that is typically protected and advertised by a trademark and trade name, and claimed to be effective against minor disorders and symptoms, [1] [2] [3] as opposed to a prescription drug that ...
The term "me-too drug" or "follow-on drug" refers to a medication that is similar to a pre-existing drug, usually by making minor modifications to the prototype, reflected in slight changes in the profiles of side effects or activity, and used to treat conditions for which drugs already exist.
Lyrica, a recent off-patent painkiller for nervous systems, had a sale of 5B USD in 2019, [38] out of the 51.8B USD annual sale of the corresponding company. [39] However, once the proprietary drug become off-patent, there will soon be immense competition from the generic drugs produced by their business rivals. [40]
In order to start selling a drug promptly after the patent on innovator drug expires, a generic company has to file its ANDA well before the patent expires. This puts the generic company at risk of being sued for patent infringement, since the act of filing the ANDA is considered "constructive infringement" of the patent. [41]
Sufentanil offers properties of sedation and can be used as analgesic component of anesthetic regimen during an operation. [9]Because of its extremely high potency, it is often used in surgery and post-operative pain management for patients that are heavily opioid dependent/opioid tolerant because of long term opiate use for chronic pain or illicit opiate use.
Tapentadol, sold under the brand names Nucynta and Palexia among others, is a synthetic opioid analgesic of the benzenoid class with a dual mode of action as a highly selective full agonist of the μ-opioid receptor and as a norepinephrine reuptake inhibitor (NRI). [7]
Simvastatin was initially marketed by Merck & Co under the brand name Zocor but is available generically in most countries following the patent expiry. [ citation needed ] A combination of simvastatin along with ezetimibe is sold under the brand name Vytorin and is jointly marketed by Merck and Schering-Plough .