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The latency stage involves few or no symptoms and can last anywhere from two weeks to twenty years or more, depending on the individual. AIDS, the final stage of HIV infection, is defined by low CD4+ T cell counts (fewer than 200 per μL), various opportunistic infections, cancers, and other conditions.
Without treatment, this second stage of the natural history of HIV infection can last from about three years [34] to over 20 years [35] (on average, about eight years). [36] While typically there are few or no symptoms at first, near the end of this stage many people experience fever, weight loss, gastrointestinal problems and muscle pains. [1]
Contracting HIV can lead to the development of AIDS or stage 3 HIV, which causes serious damage to the immune system. [medical citation needed] While this virus is the underlying cause of AIDS, [3] not all HIV-positive individuals have AIDS, as HIV can remain in a latent state for many years.
Two types of HIV have been characterized: HIV-1 and HIV-2. HIV-1 is the virus that was initially discovered and termed both lymphadenopathy associated virus (LAV) and human T-lymphotropic virus 3 (HTLV-III). HIV-1 is more virulent and more infective than HIV-2, [20] and is the cause of the majority of HIV infections globally. The lower ...
There is an initial period of influenza-like illness, and then a latent, asymptomatic phase. When the CD4 lymphocyte count falls below 200 cells/ml of blood, the HIV host has progressed to AIDS, [ 1 ] a condition characterized by deficiency in cell-mediated immunity and the resulting increased susceptibility to opportunistic infections and ...
Following infection with HIV-1, the rate of clinical disease progression varies between individuals.Factors such as host susceptibility, genetics and immune function, [1] health care and co-infections [2] as well as viral genetic variability [3] may affect the rate of progression to the point of needing to take medication in order not to develop AIDS.
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