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Neonatal jaundice is a yellowish discoloration of the white part of the eyes and skin in a newborn baby due to high bilirubin levels. [1] Other symptoms may include excess sleepiness or poor feeding. [ 1 ]
The prevalence of jaundice in adults is rare, while jaundice in babies is common, with an estimated 80% affected during their first week of life. [8] The most commonly associated symptoms of jaundice are itchiness, [2] pale feces, and dark urine. [4]
Physiologic jaundice can be a benign condition that presents in newborns until two weeks of life. [2] However, jaundice that continues after two weeks requires follow up with measurement of total and conjugated bilirubin. [3] Elevated levels of conjugated bilirubin are never benign and require further evaluation for neonatal cholestasis. [3]
The infant with neonatal hepatitis usually has jaundice that appears at one to two months of age, is not gaining weight and growing normally, and has an enlarged liver and spleen. Infants with this condition are usually jaundiced. Jaundice that is caused by neonatal hepatitis is not the same as physiologic neonatal jaundice. In contrast with ...
In both newborns and adults, yellowing of the skin is a marker for jaundice. [27] As most cases of jaundice are observed in newborns, healthcare workers use visual methods to identify the presence of this condition. [29]
Symptoms often occur in newborns as they have red blood cells with decreased lifespans and increased blood concentrations causing increased bilirubin production. [2] The most severe symptom of hyperbilirubinemia in newborns is kernicterus or death.
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Jaundice in newborns may be treated with bili lights. [2] It is recommended that people be tested for G6PDD before certain medications, such as primaquine, are taken. [2] About 400 million people have the condition globally. [1] It is particularly common in certain parts of Africa, Asia, the Mediterranean, and the Middle East. [1]