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The brush rabbit is the sole carrier of myxoma virus in North American because other native lagomorphs, including cottontail rabbits and hares, are incapable of transmitting the disease.[4][1] Clinical signs of myxomatosis depend on the strain of virus, the route of inoculation, and the immune status of the host.
Rabbit hemorrhagic disease virus (RHDV) is a virus in the genus Lagovirus and the family Caliciviridae.It is a nonenveloped virus with a diameter around 35–40 nm, icosahedral symmetry, and a linear positive-sense RNA genome of 6.4–8.5 kb.
Rabbit hemorrhagic disease (RHD), also known as viral hemorrhagic disease (VHD) or rabbit calicivirus disease (RCD), [43] is caused by a rabbit-specific calicivirus known as rabbit hemorrhagic disease virus (RHDV) or rabbit calicivirus (RCV). Discovered in 1983, RHD is highly infectious and usually fatal.
Rabbit hemorrhagic disease (RHD) is a highly infectious rabbit-specific disease caused by strains of rabbit hemorrhagic disease virus (RHDV), including type 2 (RHDV2). [112] The disease was first described in domestic Angora rabbits imported from Germany to Jiangsu , China in 1984, and quickly spread to Korea, Italy, and the rest of Europe.
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Rabbit hemorrhagic disease virus is a pathogen of rabbits that causes major problems throughout the world where rabbits are reared for food and clothing, make a significant contribution to ecosystem ecology, and where they support valued wildlife as a food source. [7]
This is the reason myxoma virus is very species-specific; it is able to circumvent a certain species of rabbit's immune response, but is unable to do so for any other species. The virus is able to get into the cells of many different species , though, including human, mouse, and monkey, which is generally useless if it is unable to replicate ...
The virus is a non-enveloped, isometric virus with diameter of around 30 nanometer. Its viral genome is 8,295 nucleotides in size, consisting of positive single-stranded RNA with a small protein (VPg) covalently linked to its 5′ terminus and a 3′ poly-A tail with an average length of 85 nucleotides.