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Contraindicated in pregnancy: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Tocolytics are used in preterm labor, which refers to when a baby is born too early before 37 weeks of pregnancy. As preterm birth represents one of the leading causes of neonatal morbidity and mortality, the goal is to prevent neonatal morbidity and mortality through delaying delivery and increasing gestational age by gaining more time for other management strategies like corticosteroids ...
[253] [254] [255] Progestogens with the potential for clinically relevant glucocorticoid effects include the 17α-hydroxyprogesterone derivatives chlormadinone acetate, cyproterone acetate, medroxyprogesterone acetate, megestrol acetate, promegestone, and segesterone acetate and the testosterone derivatives desogestrel, etonogestrel, and gestodene.
On 17 November 2004, the United States Food and Drug Administration put a black box warning on the label, indicating that there were potential adverse effects of loss of bone mineral density. [ 100 ] [ 101 ] While it causes temporary bone loss , most women fully regain their bone density after discontinuing use. [ 75 ]
Bishop score, also Bishop's score or cervix score, is a pre-labor scoring system to assist in predicting whether induction of labor will be required. [1] It has also been used to assess the likelihood of spontaneous preterm delivery. [2]
The Robson classification, also known as the 10-groups classification or ten groups classification system (TGCS), is a system for classifying pregnant women who undergo childbirth. It was developed to allow more accurate comparison of caesarean section rates between different settings, whether they be individual hospitals or entire regions or ...
Improving nutrition of female, both before and during pregnancy, is important for reducing the risk of obstructive labor. [11] Creating education programs about reproduction and increasing access to reproductive services such as contraception and family planning in developing areas can also reduce the prevalence of obstructed labor.
Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [ 2 ] [ 3 ] [ 4 ] Salts of this anion, especially docusate sodium , are widely used in medicine as an emollient laxative and as stool softeners , by mouth or rectally. [ 1 ]