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Prucalopride, a first in class dihydro-benzofuran-carboxamide, is a selective, high affinity serotonin (5-HT 4) receptor agonist with enterokinetic activities. [29] Prucalopride alters colonic motility patterns via serotonin 5-HT 4 receptor stimulation: it stimulates colonic mass movements, which provide the main propulsive force for defecation .
Signs and symptoms of pregnancy are common, benign conditions that result from the changes to the body that occur during pregnancy. Signs and symptoms of pregnancy typically change as pregnancy progresses, although several symptoms may be present throughout. Depending on severity, common symptoms in pregnancy can develop into complications. [1 ...
If you're experiencing the first symptoms of pregnancy or wondering when pregnancy symptoms start, you can look forward to week 13, or the start of the second trimester, when early pregnancy ...
Contraindicated in pregnancy: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Intrahepatic cholestasis of pregnancy (ICP), also known as obstetric cholestasis, cholestasis of pregnancy, jaundice of pregnancy, and prurigo gravidarum, [1] is a medical condition in which cholestasis occurs during pregnancy. [2] It typically presents with itching and can lead to complications for both mother and fetus. [2]
Pre-eclampsia is a multi-system disorder specific to pregnancy, characterized by the new onset of high blood pressure and often a significant amount of protein in the urine or by the new onset of high blood pressure along with significant end-organ damage, with or without the proteinuria.
Sydenham's chorea, of which chorea gravidarum is a severe variant, has a number of psychiatric complications, which include psychosis. This usually develops during pregnancy, and occasionally after the birth or abortion. Its symptoms include severe hypnagogic hallucinations , [130] [131] possibly the result of the extreme sleep disorder. This ...
[62] [63] [64] Conversely, research on combined estrogen and progestogen therapy for depressive symptoms in menopausal women is scarce and inconclusive. [ 62 ] [ 63 ] Some researchers contend that progestogens have an adverse influence on mood and reduce the benefits of estrogens on mood, [ 65 ] [ 66 ] [ 2 ] whereas other researchers maintain ...