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Thromboelastography (TEG) is a method of testing the efficiency of blood coagulation. It is a test mainly used in surgery and anesthesiology , although increasingly used in resuscitations in emergency departments, intensive care units, and labor and delivery suites.
The pathophysiology of acute respiratory distress syndrome involves fluid accumulation in the lungs not explained by heart failure (noncardiogenic pulmonary edema). It is typically provoked by an acute injury to the lungs that results in flooding of the lungs' microscopic air sacs responsible for the exchange of gases such as oxygen and carbon dioxide with capillaries in the lungs. [1]
[1] [2] It is the most widely used TGA. [3] The CAT is a semi-automated test performed in a 96-well plate and requires specialized technologists to be performed. [ 3 ] As a result, it has seen low implementation in routine laboratories and has been more limited to research settings.
Thromboelastometry (TEM), previously named rotational thromboelastography (ROTEG) or rotational thromboelastometry (ROTEM), is an established viscoelastic method for hemostasis testing in whole blood. [1] It is a modification of traditional thromboelastography (TEG).
Globally, ARDS affects more than 3 million people a year. [1] The condition was first described in 1967. [ 1 ] Although the terminology of "adult respiratory distress syndrome" has at times been used to differentiate ARDS from " infant respiratory distress syndrome " in newborns, the international consensus is that "acute respiratory distress ...
Diffuse alveolar damage (DAD) is a histologic term used to describe specific changes that occur to the structure of the lungs during injury or disease.Most often DAD is described in association with the early stages of acute respiratory distress syndrome (). [1]
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It is often impossible to distinguish TRALI from acute respiratory distress syndrome (ARDS). The typical presentation of TRALI is the sudden development of shortness of breath, severe hypoxemia (O 2 saturation <90% in room air), low blood pressure, and fever that develop within 6 hours after transfusion and usually resolve with supportive care within 48 to 96 hours.