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Valaciclovir, also spelled valacyclovir, is an antiviral medication used to treat outbreaks of herpes simplex or herpes zoster (shingles). [2] It is also used to prevent cytomegalovirus following a kidney transplant in high risk cases. [2] It is taken by mouth. [2] Common side effects include headache and vomiting. [2]
In epidemiology, an outbreak is a sudden increase in occurrences of a disease when cases are in excess of normal expectancy for the location or season. It may affect a small and localized group or impact upon thousands of people across an entire continent.
An immunity to the virus is built over time. Most infected individuals experience fewer outbreaks and outbreak symptoms often become less severe. After several years, some people become perpetually asymptomatic and no longer experience outbreaks, though they may still be contagious to others. Immunocompromised individuals may experience longer ...
A breakthrough infection is a case of illness in which a vaccinated individual becomes infected with the illness, because the vaccine has failed to provide complete immunity against the pathogen (currently only viruses). [1]
Ongoing epidemics and pandemics are in boldface.For a given epidemic or pandemic, the average of its estimated death toll range is used for ranking. If the death toll averages of two or more epidemics or pandemics are equal, then the smaller the range, the higher the rank.
About 16 percent of Americans between the ages of 14 and 49 are infected with genital herpes, making it one of the most common sexually transmitted infections. [26] More than 85% of those with HSV-2 are unaware of their infection. [27] Approximately 776,000 people in the United States get new herpes infections every year. [27]
Common source outbreak of Hepatitis A in Nov-Dec 1978. This epidemic curve shows a presumed first case, known as the index case on November 6, 1978. 4 days later, there was a steep increase in cases, followed by the curve tapering down to zero. Some cases were food handlers, and some secondary cases.
An outbreak can be preceded by months of such tension, which then results in physical symptoms such as seen in Musoli. Far from faking it, “Under such prolonged stress, the nerves and neurons that send messages to the brain become disrupted, resulting in an array of neurological symptoms such as twitching, shaking, convulsions, and trance ...