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Severe side effects may include kidney problems. [2] Use in pregnancy appears to be safe. [2] It is a prodrug, which works after being converted to aciclovir in a person's body. [2] Valaciclovir was patented in 1987 and came into medical use in 1995. [3] [4] It is on the World Health Organization's List of Essential Medicines. [5]
Liver diseases, including conditions such as non-alcoholic fatty liver disease (NAFLD), alcohol-related liver disease (ALD), and viral hepatitis, are significant public health concerns worldwide. In the United States, NAFLD is the most common chronic liver condition, affecting approximately 24% of the population, with the prevalence rising due ...
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.
Infectious disease, gastroenterology Herpes esophagitis is a viral infection of the esophagus caused by Herpes simplex virus (HSV). While the disease most often occurs in immunocompromised patients, including post- chemotherapy , immunosuppression with organ transplants [ 1 ] and in AIDS , [ 2 ] herpes esophagitis can also occur in ...
Ischemic hepatitis, also known as shock liver, is a condition defined as an acute liver injury caused by insufficient blood flow (and consequently insufficient oxygen delivery) to the liver. [5] The decreased blood flow ( perfusion ) to the liver is usually due to shock or low blood pressure.
Esophageal diseases can derive from congenital conditions, or they can be acquired later in life.. Many people experience a burning sensation in their chest occasionally, caused by stomach acids refluxing into the esophagus, normally called heartburn.