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The tunica externa (Neo-Latin "outer coat"), also known as the tunica adventitia (Neo-Latin "additional coat"), [1] [2] is the outermost tunica (layer) of a blood vessel, surrounding the tunica media. It is mainly composed of collagen and, in arteries, is supported by external elastic lamina. The collagen serves to anchor the blood vessel to ...
The outer layer is the tunica adventitia and the thickest layer in veins. It is entirely made of connective tissue. It is entirely made of connective tissue. It also contains nerves that supply the vessel as well as nutrient capillaries ( vasa vasorum ) in the larger blood vessels.
The three layers of a blood vessel are an inner layer (the tunica intima), a middle layer (the tunica media), and an outer layer (the tunica externa). In dissection , the inner coat (tunica intima) can be separated from the middle (tunica media) by a little maceration, or it may be stripped off in small pieces; but, because of its friability ...
In the largest vessels, the vasa vasorum penetrates the outer (tunica adventitia) layer and middle (tunica media) layer almost to the inner (tunica intima) layer. In smaller vessels it penetrates only the outer layer. In the smallest vessels, the vessels' own circulation nourishes the walls directly and they have no vasa vasorum at all.
Micrograph showing the internal elastic lamina (thin pink wavy line - image edge mid-left to image edge bottom-centre-left). H&E stain.. The internal elastic lamina or internal elastic lamella is a layer of elastic tissue that forms the outermost part of the tunica intima of blood vessels.
The layers known as tunicae have a concentric arrangement that forms the wall of the vessel. The outer layer, is a thick layer of connective tissue called the tunica externa or adventitia; this layer is absent in the post-capillary venules. [4] The middle layer, consists of bands of smooth muscle and is known as the tunica media.
The muscle fiber cells are arranged in 5 to 7 layers of circular and longitudinal smooth muscle with about 50μ in length and contain well-marked, rod-shaped nuclei, which are often slightly curved. Separating the tunica media from the outer tunica externa in larger arteries is the external elastic membrane (also called the external elastic ...
The innermost layer, which is in direct contact with the flow of blood, is the tunica intima. The elastic tissue allows the artery to bend and fit through places in the body. This layer is mainly made up of endothelial cells (and a supporting layer of elastin rich collagen in elastic arteries).