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Generally, a splinter causes an initial feeling of pain as the sharp object makes its initial penetration through the body. Through this penetration, the object cuts through the cutaneous layer of the skin, and settles in the subcutaneous layer of the skin, and can even penetrate further down, breaking the sub-cutaneous layer, settling in muscle tissue, or even the bone.
A foreign-body granuloma occurs when a foreign body (such as a wood splinter, piece of metal, glass etc.) penetrates the body's soft tissue followed by acute inflammation and formation of a granuloma. [18] In some cases the foreign body can be found and removed even years after the precipitating event. [19]
Tissue encapsulation of an implant is an example, as is inflammation around a splinter. [3] Foreign body granuloma formation consists of protein adsorption, macrophages, multinucleated foreign body giant cells (macrophage fusion), fibroblasts, and angiogenesis. It has also been proposed that the mechanical property of the interface between an ...
Immediately after intense exercise there is a transient immunodepression, where the number of circulating lymphocytes decreases and antibody production declines. This may give rise to a window of opportunity for infection and reactivation of latent virus infections, [104] but the evidence is inconclusive. [105] [106]
The mycophagous phase of the life cycle takes place in dead or dying wood, where the nematodes live and feed upon fungi, rather than the wood itself. The nematode cannot travel outside of the wood independently; it must be transported by an insect vector. B. xylophilus has the shortest life cycle of any known parasitic nematode. In laboratory ...
A skin infection is an infection of the skin in humans and other animals, that can also affect the associated soft tissues such as loose connective tissue and mucous membranes. [ citation needed ] They comprise a category of infections termed skin and skin structure infections (SSSIs), or skin and soft tissue infections (SSTIs), [ 1 ] and acute ...
Skin and skin structure infections (SSSIs), also referred to as skin and soft tissue infections (SSTIs), [1] or acute bacterial skin and skin structure infections (ABSSSIs), [2] are infections of skin and associated soft tissues (such as loose connective tissue and mucous membranes).
Infection on the skin of the feet may cause athlete's foot and in the groin, jock itch. Involvement of the nails is termed onychomycosis . Animals including dogs and cats can also be affected by ringworm, and the disease can be transmitted between animals and humans, making it a zoonotic disease .