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  2. Central nervous system depression - Wikipedia

    en.wikipedia.org/wiki/Central_nervous_system...

    Central nervous system (CNS) depression is a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness, possibly leading to coma or death. It is the result of inhibited or suppressed brain activity .

  3. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    Sleep deprivation and light therapy both target the same brain neurotransmitter system and brain areas as antidepressant drugs, and are now used clinically to treat depression. [28] Light therapy, sleep deprivation and sleep time displacement (sleep phase advance therapy) are being used in combination quickly to interrupt a deep depression in ...

  4. Brodmann area 25 - Wikipedia

    en.wikipedia.org/wiki/Brodmann_area_25

    This region is extremely rich in serotonin transporters and is considered as a governor for a vast network involving areas like hypothalamus and brain stem, which influences changes in appetite and sleep; the amygdala and insula, which affect the mood and anxiety; the hippocampus, which plays an important role in memory formation; and some parts of the frontal cortex responsible for self ...

  5. Long-term depression - Wikipedia

    en.wikipedia.org/wiki/Long-term_depression

    In neurophysiology, long-term depression (LTD) is an activity-dependent reduction in the efficacy of neuronal synapses lasting hours or longer following a long patterned stimulus. LTD occurs in many areas of the CNS with varying mechanisms depending upon brain region and developmental progress.

  6. Depression and immune function - Wikipedia

    en.wikipedia.org/wiki/Depression_and_immune_function

    [7] [65] There is also initial evidence that major depression and stress can alter the permeability of the blood-brain barrier, allowing substances which would normally not be able to pass through enter the brain, thereby increasing the ways peripheral inflammation can affect the brain. [65] [79]

  7. Mood disorder - Wikipedia

    en.wikipedia.org/wiki/Mood_disorder

    Family history, previous diagnosis of a mood disorder, trauma, stress or major life changes in the case of depression, physical illness or use of certain medications. Depression has been linked to major diseases such as cancer, diabetes, Parkinson's disease and heart disease, Brain structure and function in the case of bipolar disorder. [1 ...

  8. Major depressive disorder - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_disorder

    This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...

  9. Central nervous system - Wikipedia

    en.wikipedia.org/wiki/Central_nervous_system

    The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain, spinal cord and retina.The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and diploblasts.