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The CC chemokine (or β-chemokine) proteins have two adjacent cysteines (amino acids), near their amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called CC chemokine ligands -1 to -28; CCL10 is the same as CCL9. Chemokines of this subfamily usually contain four cysteines (C4-CC chemokines ...
1230 12768 Ensembl ENSG00000163823 ENSMUSG00000025804 UniProt P32246 P51675 RefSeq (mRNA) NM_001295 NM_009912 RefSeq (protein) NP_001286 NP_034042 Location (UCSC) Chr 3: 46.2 – 46.21 Mb Chr 9: 123.76 – 123.77 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse C-C chemokine receptor type 1 is a protein that in humans is encoded by the CCR1 gene. CCR1 has also recently been designated ...
CC chemokine receptors (or beta chemokine receptors) are integral membrane proteins that specifically bind and respond to cytokines of the CC chemokine family. They represent one subfamily of chemokine receptors, a large family of G protein-linked receptors that are known as seven transmembrane (7-TM) proteins since they span the cell membrane seven times.
C-C chemokine receptor type 2 (CCR2 or CD192 (cluster of differentiation 192) is a protein that in humans is encoded by the CCR2 gene. [5] CCR2 is a CC chemokine receptor . Gene
In the human genome, CCL2 and many other CC chemokines are located on chromosome 17 (17q11.2-q21.1). [8] The gene span is 1,927 bases and the CCL2 gene resides on the Watson (plus) strand. The CCL2 gene has three exons and two introns. The CCL2 protein precursor contains a signal peptide of 23 amino acids. In turn, the mature CCL2 is 76 amino ...
The CCR 3 receptor is a CC chemokine receptor that is a 7-transmembrane, G-linked protein receptor. This receptor is primarily found on eosinophils and basophils. The CCR 3 receptor is what regulates the eotaxin's activity. It does this through selective expression. When eotaxin binds with the CCR 3 Receptor, it induces biological changes.
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