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Note the premature arterial calcification which is a clue that this is a renal patient. Vascular calcification contributes to an increase in morbidity. Tumoral calcinosis is a rare condition in which there is calcium deposition in the soft tissue in periarticular location, around joints , outside the joint capsule . [ 1 ]
Dystrophic calcification (DC) is the calcification occurring in degenerated or necrotic tissue, as in hyalinized scars, degenerated foci in leiomyomas, and caseous nodules. This occurs as a reaction to tissue damage, [ 1 ] including as a consequence of medical device implantation.
Popcorn calcification or popcorn appearance is the radiological appearance of calcification with irregular rings and arcs, which resembles popcorns.The calcification patterns in chondroid lesions of the bone (such as enchondroma and chondrosarcoma), [1] pulmonary hamartomas, [2] degenerating fibroadenomas of the breast and calcified fibroids of the uterus have been described as 'popcorn ...
High magnification micrograph of giant cells in a giant-cell tumor of bone, H&E stain. The diagnosis of giant-cell tumors is based on biopsy findings. The key histomorphologic feature is, as the name of the entity suggests, (multinucleated) giant cells with up to a hundred nuclei that have prominent nucleoli.
In contrast, dystrophic calcification is caused by abnormalities or degeneration of tissues [2] [3] resulting in mineral deposition, though blood levels of calcium remain normal. These differences in pathology also mean that metastatic calcification is often found in many tissues throughout a person or animal, whereas dystrophic calcification ...
Calcinosis cutis is an uncommon condition marked by calcium buildup in the skin and subcutaneous tissues. Calcinosis cutis can range in intensity from little nodules in one area of the body to huge, crippling lesions affecting a vast portion of the body. [1]
The differential diagnosis includes many tumoral and nontumoral pathologies. A main concern is to differentiate early myositis ossificans from malignant soft-tissue tumors, and the latter is suggested by a fast-growing process. If clinical or sonographic findings are dubious and extraosseous sarcoma is suspected, biopsy should be performed.
Mammogram microcalcifications in ductal carcinoma in situ. Microcalcifications are tiny deposits of calcium salts that are too small to be felt but can be detected by imaging. [1] They can be scattered throughout the mammary gland, or occur in clusters. Microcalcifications can be an early sign of breast cancer. Based on morphology, it is ...