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  2. Acid–base homeostasis - Wikipedia

    en.wikipedia.org/wiki/Acidbase_homeostasis

    Acid–base homeostasis is the homeostatic regulation of the pH of the body's extracellular fluid (ECF). [1] The proper balance between the acids and bases (i.e. the pH) in the ECF is crucial for the normal physiology of the body—and for cellular metabolism . [ 1 ]

  3. Davenport diagram - Wikipedia

    en.wikipedia.org/wiki/Davenport_diagram

    Recall that the relationship represented in a Davenport diagram is a relationship between three variables: P CO 2, bicarbonate concentration and pH.Thus, Fig. 7 can be thought of as a topographical map—that is, a two-dimensional representation of a three-dimensional surface—where each isopleth indicates a different partial pressure or “altitude.”

  4. pH - Wikipedia

    en.wikipedia.org/wiki/PH

    In living organisms, the pH of various Body fluids, cellular compartments, and organs is tightly regulated to maintain a state of acid-base balance known as acid–base homeostasis. Acidosis , defined by blood pH below 7.35, is the most common disorder of acid–base homeostasis and occurs when there is an excess of acid in the body.

  5. Bicarbonate buffer system - Wikipedia

    en.wikipedia.org/wiki/Bicarbonate_buffer_system

    Most of the carbonic acid then dissociates to bicarbonate and hydrogen ions. The bicarbonate buffer system is an acid-base homeostatic mechanism involving the balance of carbonic acid (H 2 CO 3), bicarbonate ion (HCO − 3), and carbon dioxide (CO 2) in order to maintain pH in the blood and duodenum, among other tissues, to support proper ...

  6. Free base - Wikipedia

    en.wikipedia.org/wiki/Free_base

    Free base (freebase, free-base) is a descriptor for the neutral form of an amine commonly used in reference to illicit drugs. The amine is often an alkaloid , such as nicotine , cocaine , morphine , and ephedrine , or derivatives thereof.

  7. Renal compensation - Wikipedia

    en.wikipedia.org/wiki/Renal_compensation

    Respiratory and renal changes in acid-base elimination typically contrast each other, and respiratory pH disturbances often commence renal compensation. [3] The renal compensation process usually takes a few days to complete as it is dependent upon changes in the reabsorption of bicarbonate. [4]

  8. Hyperchloremic acidosis - Wikipedia

    en.wikipedia.org/wiki/Hyperchloremic_acidosis

    In general, the cause of a hyperchloremic metabolic acidosis is a loss of base, either a gastrointestinal loss or a renal loss [citation needed]. Gastrointestinal loss of bicarbonate (HCO − 3) [citation needed] Severe diarrhea (vomiting will tend to cause hypochloraemic alkalosis) Pancreatic fistula with loss of bicarbonate rich pancreatic fluid

  9. Acidosis - Wikipedia

    en.wikipedia.org/wiki/Acidosis

    The amount of metabolic acid accumulating can also be quantitated by using buffer base deviation, a derivative estimate of the metabolic as opposed to the respiratory component. In hypovolemic shock for example, approximately 50% of the metabolic acid accumulation is lactic acid, which disappears as blood flow and oxygen debt are corrected.