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  2. Acanthosis nigricans - Wikipedia

    en.wikipedia.org/wiki/Acanthosis_nigricans

    Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [ 2 ] such as the posterior and lateral folds of the neck , the armpits , groin , navel , forehead and other areas.

  3. HAIR-AN syndrome - Wikipedia

    en.wikipedia.org/wiki/HAIR-AN_syndrome

    Polydipsia, polyuria (symptoms of insulin resistance are often subclinical) Acanthosis nigricans Verrucous, velvety hyperpigmentation on nape of neck, vulva, axillae, groin, umbilicus, submammary regions; increased skin tags Obesity Increased waist-to-hip ratio (android appearance)

  4. Crouzonodermoskeletal syndrome - Wikipedia

    en.wikipedia.org/wiki/Crouzonodermoskeletal_syndrome

    Crouzonodermoskeletal syndrome is a disorder characterized by the premature joining of certain bones of the skull (craniosynostosis) during development and a skin condition called acanthosis nigricans. [1] Some of the signs and symptoms of Crouzonodermoskeletal syndrome are similar to those seen with Crouzon syndrome.

  5. Insulin Resistance: From Symptoms to Treatment - AOL

    www.aol.com/insulin-resistance-symptoms...

    But some people develop prediabetes symptoms such as: Acanthosis nigricans. These are characterized by dark patches within skin folds in locations like the neck, armpits, or groin.

  6. Florid cutaneous papillomatosis - Wikipedia

    en.wikipedia.org/wiki/Florid_cutaneous_papillo...

    Malignant acanthosis nigricans may also become evident, many times with the sudden eruption of multiple seborrheic keratoses, known as the sign of Leser-Trélat. [ 9 ] [ 10 ] [ 11 ] Florid cutaneous papillomatosis mandates a search for an underlying malignancy, recognizing that it may be seen in patients with multiple visceral carcinomas.

  7. Rabson–Mendenhall syndrome - Wikipedia

    en.wikipedia.org/wiki/Rabson–Mendenhall_syndrome

    A skin abnormality known as acanthosis nigricans, which involves a discoloration (hyperpigmentation) and "velvety" thickening (hyperkeratosis) of the skin around skin fold regions of the neck, groin and under arms is also a common symptom. [1] Symptoms will negatively impact the daily life of the patient, and will persist until treated.

  8. Leser–Trélat sign - Wikipedia

    en.wikipedia.org/wiki/Leser–Trélat_sign

    In some cases, paraneoplastic acanthosis nigricans (35% of patients), florid cutaneous papillomatosis, ichthyosis acquisita (acquired hypertrichosis lanuginosa), Cowden syndrome, tylosis, acrokeratosis paraneoplastica of Bazex or tripe palms accompany the sign of Leser–Trélat.

  9. Acanthosis nigricans-muscle cramps-acral enlargement syndrome

    en.wikipedia.org/wiki/Acanthosis_nigricans...

    Acanthosis nigricans-muscle cramps-acral enlargement syndrome, also known as Acanthosis nigricans-insulin resistance-muscle cramps-acral enlargement syndrome is an extremely rare genetic disorder which is characterized by the appearance of acanthosis nigricans, insulin resistance, muscle cramps of severe intensity, and acral hypertrophy ...