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This lack of a cure or vaccine is a definite problem in the equine industry, especially in developing countries where equines are highly valuable for both agriculture and transportation. [5] Dourine is considered an endemic problem in developing countries, where over sixty percent of equines in the world are located. [ 4 ]
It is normally injected intramuscularly, though can also be injected intra-articularily (directly into the joint) in horses or subcutaneously in off-label uses. [2] Giving PSGAG intra-articularily requires it to be given aseptically , [ 8 ] and is sometimes supplemented by the antibiotic amikacin to prevent infection.
Moxidectin is an anthelmintic drug used in animals to prevent or control parasitic worms , such as heartworm and intestinal worms, in dogs, cats, horses, cattle, sheep and wombats. [4] Moxidectin kills some of the most common internal and external parasites by selectively binding to a parasite's glutamate-gated chloride ion channels .
A vaccine is available for horses. [1] This vaccine is an inactivated vaccine that uses the TC-83 strain of EEEV. [13] It is usually given in combination with vaccines for Western equine encephalitis (WEE), Venezuelan equine encephalitis (VEE), and tetanus, [4] and is also used by
The principle of antivenom is based on that of vaccines, developed by Edward Jenner; however, instead of inducing immunity in the person directly, it is induced in a host animal and the hyperimmunized serum is transfused into the person. [20] The host animals may include horses, donkeys, goats, sheep, rabbits, chickens, llamas, and camels. [21]
Anti-thymocyte globulin (ATG) is an infusion of horse or rabbit-derived antibodies against human T cells and their precursors , which is used in the prevention and treatment of acute rejection in organ transplantation and therapy of aplastic anemia due to bone marrow insufficiency.
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