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Fluoride toxicity is a condition in which there are elevated levels of the fluoride ion in the body. Although fluoride is safe for dental health at low concentrations, [ 1 ] sustained consumption of large amounts of soluble fluoride salts is dangerous.
Soluble fluoride salts, of which sodium fluoride is the most common, are toxic, and have resulted in both accidental and self-inflicted deaths from acute poisoning. [4] The lethal dose for most adult humans is estimated at 5 to 10 g (which is equivalent to 32 to 64 mg elemental fluoride per kg body weight).
Most patients with skeletal fluorosis show side effects from the high fluoride dose such as ruptures of the stomach lining and nausea. [3] Fluoride can also damage the parathyroid glands, leading to hyperparathyroidism, the uncontrolled secretion of parathyroid hormones. These hormones regulate calcium concentration in the body.
Fluoride is a mainstay of dental care, whether it's delivered in a treatment at your dentist's office or in your toothpaste. But fluoride has become the focus of several conspiracy theories over ...
However, detractors focus on research suggesting toxic effects of fluoride at high levels, concerned that it may be harmful even at low levels. Kennedy plans to “advise all U.S. water systems to ...
The U.S. Public Health Service’s recommendation is a fluoride concentration of 0.7 mg/L of drinking water—and there were not enough data to determine if 0.7 mg/L of fluoride exposure in ...
Ingested fluoride forms hydrofluoric acid in the stomach. In this form, fluoride crosses cell membranes and then binds with calcium and interferes with various enzymes. Fluoride is excreted through urine. Fluoride exposure limits are based on urine testing, which is used to determine the human body's capacity for ridding itself of fluoride. [69 ...
That doesn't mean the water is fluoride-free: According to the Los Angeles Department of Water and Power, the city's groundwater contains fluoride at concentrations ranging from 0.1 to 0.3 mg/L ...