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7352 22229 Ensembl ENSG00000175564 ENSMUSG00000032942 UniProt P55916 P56501 RefSeq (mRNA) NM_022803 NM_003356 NM_009464 RefSeq (protein) NP_003347 NP_073714 NP_033490 Location (UCSC) Chr 11: 74 – 74.01 Mb Chr 7: 100.12 – 100.14 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Mitochondrial uncoupling protein 3 is a protein that in humans is encoded by the UCP3 gene. The gene is ...
In contrast to UCP1 and UCP3, which are primarily expressed in adipose and smooth muscle, UCP2 is expressed on many different tissues [6] including the kidney, liver, GI tract, brain, and skeletal muscle. The exact mechanisms of anion transfer by UCPs are not known. [7] UCPs contain the three homologous protein domains of MACPs.
Barbara Cannon is a British-Swedish biochemist, physiologist and an academic.She is an emeritus professor at Stockholm University [1] as well as the chairman of the scientific advisory board at The Helmholtz Centre.
The 3′-untranslated region plays a crucial role in gene expression by influencing the localization, stability, export, and translation efficiency of an mRNA. It contains various sequences that are involved in gene expression, including microRNA response elements (MREs), AU-rich elements (AREs), and the poly(A) tail.
22227 Ensembl ENSG00000109424 ENSMUSG00000031710 UniProt P25874 P12242 RefSeq (mRNA) NM_021833 NM_009463 RefSeq (protein) NP_068605 NP_033489 Location (UCSC) Chr 4: 140.56 – 140.57 Mb Chr 8: 84.02 – 84.03 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Thermogenin (called uncoupling protein by its discoverers and now known as uncoupling protein 1, or UCP1) is a mitochondrial ...
269523 Ensembl ENSG00000165280 ENSMUSG00000028452 UniProt P55072 Q01853 RefSeq (mRNA) NM_007126 NM_001354927 NM_001354928 NM_009503 RefSeq (protein) NP_009057 NP_001341856 NP_001341857 NP_033529 Location (UCSC) Chr 9: 35.05 – 35.07 Mb Chr 4: 42.98 – 43 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Valosin-containing protein (VCP) or transitional endoplasmic reticulum ATPase ...
Mitochondrial uncoupling protein 4 is a protein that in humans is encoded by the SLC25A27 gene. [5] [6] [7]Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP).
[5] [6] In humans, the Bcl-2-binding component 3 protein is encoded by the BBC3 gene. [5] [6] The expression of PUMA is regulated by the tumor suppressor p53. PUMA is involved in p53-dependent and -independent apoptosis induced by a variety of signals, and is regulated by transcription factors, not by post-translational modifications.