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Dental fluorosis is caused by a higher than normal amount of fluoride ingestion whilst teeth are forming. Primary dentine fluorosis and enamel fluorosis can only happen during tooth formation, so fluoride exposure occurs in childhood. Enamel fluorosis has a white opaque appearance which is due to the surface of the enamel being hypomineralised ...
Skeletal fluorosis is a bone disease caused by excessive accumulation of fluoride leading to weakened bones. [1] In advanced cases, skeletal fluorosis causes painful damage to bones and joints . Symptoms
Patients with reduced salivary flow are at an increased risk of tooth decay. The home application of 1.1% fluoride gel with a custom tray is recommended for patients undergoing or are finished with head and neck radiation treatment and patients with decreased salivary flow. [59]
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It's true that too much fluoride can be dangerous — one complication is skeletal fluorosis, which causes stiffening and pain of the joints and bones or abdominal pain, nausea and vomiting ...
Fluoride or fluorine deficiency is a disorder which may cause increased dental caries [1] and possibly osteoporosis, [2] [3] due to a lack of fluoride in diet. [4] [5] Common dietary sources of fluoride include tea, grape juice, wine, raisins, some seafood, coffee, and tap water that has been fluoridated. [6]
The primary endpoint of ICARIA-MM was progression-free survival (PFS). Key secondary endpoints included ORR and OS. About the IsaFiRsT study The IsaFiRsT study was a single-arm, observational, prospective, real-world study evaluating Sarclisa in combination with Pd in patients with R/R MM. The study enrolled 24 patients with R/R MM at one site ...
The Dallas Cowboys requested permission to interview Philadelphia Eagles offensive coordinator Kellen Moore for their vacant head coaching position, multiple media outlets reported Thursday.